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Neurobiol Dis 34(2):279290 Cirrik S, Hacioglu G, Kabartan E, Tezcan Yavuz B, Sirin TC (2024) Can Alpha-pinene prevent methotrexate-induced cardiac and hepatic damage

Hyperglycemia, increased sorbitol and protein kinase C, elevated homocysteine, reduced nitric oxide and excessive Reactive Oxygen Species (ROS) damage endothelial tissue and produce a rheological change that increases vascular resistance and reduces blood flow to the nerve 3.3 Risk factors Diabetes is the strongest risk factor for DPN, along with certain disease characteristics such as diabetes duration and poor glycemic control in terms of fasting blood glucose (FBG), glycated hemoglobin (HbA1c

A conjugate according to claim 1 or 2, wherein the ligand is a ligand that specifically binds to or is endocytosed or transcytosed into or through a BCEC or MDCK target cell at a rate that is at least 10% enhanced as compared control conditions selected from a) cells lacking expression of GSH transporters

My answer was, I don't think it extends lifespan